Expression of Gastric Carcinoma Related Antigen inDifferent Types of Intestinal Metaplasia Definedby Monoclonal Antibody MG7
- VernacularTitle:胃癌单克隆抗体MG7相应抗原在不同型肠化组织中的表达
- Author:
Dianchun FANG
;
Weiwen LIU
- Publication Type:Journal Article
- Keywords:
stomach neoplasms;
metaplasia;
antibodies, monoclonal;
immu-nochemistry
- From:Journal of Third Military Medical University
1983;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
The expression of gastric carcinoma related antigen was observed in 110 gastrectomy specimens with gastric carcinoma and 343 biopsy specimens with intestinal metaplasia by ABC immunohistochemical staining with MG 7 , a monoclonal antibody against human gastric carcinoma. Intestinal metaplasia was classified into types I, II and III by histochemical mucin stainings. Among the 110 cases of gastric carcinomas, 92 (83.6%) showed the positive reaction for MG 7 related antigen. In different types of intestinal metaplasia, type III (46.7%) exhibited a significantly higher positive rate for MG 7 related antigen than type II (25.6%) and type I (18.6%) (P
