THE ANTIOXIDANT ACTION OF MALTOL ON ERYTHROCYTE MEMBRANE
- VernacularTitle:麦芽醇抗人红细胞膜氧化的研究
- Author:
Limin FENG
;
Fubao LIN
;
Huazhen PAN
- Publication Type:Journal Article
- Keywords:
Erythrocyte membrane;
Oxygen free radical;
Antioxidant;
Maltol
- From:
Chinese Pharmacological Bulletin
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Maltol is a chemical derived from Chinese herb Panax Ginseng. The effect of maltol on hemolysis and hydroperoxidation of erythro-cytes induced by active oxygen radical is presented. Maltol could protect hemolysis induced by H2O2 in vitro. When erythrocyte membrane protein was exposed to butylhydroperoxide in vitro, membrane protein was polymerized, and membrane lipids were oxidized to hydroperoxide compound. These oxidative reactions could inhibited by maltol. The results showed that maltol might act as a scavenger of superoxide of hydroxy radical as demonstrated by biochemical method and ESR spin method。
