EFFECTS OF THIOPROLINE ON THROMBUS FORMATION AND PLATELET FUNCTION
- VernacularTitle:硫代脯氨酸对血栓形成和血小板功能的影响
- Author:
Yibin HAO
;
Erfeng ZHOU
;
Yunzhao TANG
;
Yueqing LIANG
- Publication Type:Journal Article
- Keywords:
Thioproline;
Thrombus formation;
Platelet adhesion;
Platelet aggregation
- From:
Chinese Pharmacological Bulletin
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Effects of thioproline on thrombus formation and platelet function were studied. Thioprolline given in vitro ( 1 g/L ) or ex vivo ( iv 25mg /kg ) shortened length of thrombi and decresed the wet and dry weight of thrombi in rabbits or rats. Thioproline given iv vitro ( 1 g/L ) or ex vivo ( iv 50mg/kg ) inhibited platelet adhesion and aggregation induced by ADP in rabbits.
