INFLUENCE OF ZINC DEFICIENCY ON METABOLISM OF VITAMIN A IN RATS
- VernacularTitle:缺锌对大鼠维生素A代谢的影响
- Author:
Baowu WANG
;
Jingfan GU
- Publication Type:Journal Article
- Keywords:
zinc deficiency zinc treatment vitamin A metabolism
- From:
Acta Nutrimenta Sinica
1956;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
The study includes 2 experiments. Experiment 1: 24 male weanling Wistar rats were divided into 3 groups, with 8 rats in each group:zinc-deficient group (ZD), pair-fed group (PF), zinc-sufficient group (ZS). The experiment term was 30 days, and the items observed were feed intake, body weight, serum zinc, tibia zinc, serum vitamin A and liver vitamin A. The results showed that Zn-deficient rats could not mobilize liver vitamin A into their blood normally. Experiment 2; 40 male weanling Wistar rats were raised with Zn-deficient feed for 30 days, then they were divided into 4 groups randomly, keeping 7 rats in each group:Zn-deficient group (ZD), Zn-treatment group I(ZT1), Zn-treatment group II(ZT2), Zn-treatment group III(ZT3), their daily Zn dosages were 0.63 umol, 1,89 umol, 3.80 umol respectively. The treatment lasted for 6 days. The results demonstrated that serum zinc and vitamin A concentrations of the 3 Zn-treated groups were much higher than that of ZD group. In contrast, their liver vitamin A concentrations were much lower than that of ZD group.
