EFFECT OF VERAPAMIL AND NIFEDIPINE ON OVIDUCT MOTILITY AND OVUM TRANSPORT IN RAT
- VernacularTitle:维拉帕米、硝苯吡啶对大鼠输卵管活动和卵转运的影响
- Author:
Yuanxiu XU
;
Hanqin LEI
;
Min JU
- Publication Type:Journal Article
- Keywords:
Calcium blockers;
Verapamil;
Nifedipne;
Oviduct;
Ovum transport;
Anti-implantation
- From:
Chinese Pharmacological Bulletin
1987;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Calcium blockers verapamil ( VER ) and nifedipine ( NIF ) appa-rentely inhibited the spontaneous activity of isolated rat oviduct. The 5 min contractile curve aera determined by integrator,after eithet VER or NIF effected, was smaller than that before,with dose dependence.In rats pregnanant for 3d VER and NIF accelerated ovum transport through oviduct. The number of ovum recovered from uterus in test group was more than that in control group. Paired experiments showed VER and NIF having no anti-implantation action.
