ANTAGONISM OF TETRAMETHYLPYRAZINE TO ASTHMOGENIC MEDIATORS ON CONTRACTION OF ISOLATED GUINEA PIG TRACHEA
- VernacularTitle:川芎嗪对几种致喘介质所致离体豚鼠气管条收缩作用的影响
- Author:
Ruixiang ZHANG
;
Jinnong ZHANG
;
Xiaonan TAO
- Publication Type:Journal Article
- Keywords:
Tetramethylpyrazine;
Asthmogenic mediators;
Contraction of trachea
- From:
Chinese Pharmacological Bulletin
1987;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
The effects of tetramethylpyrazine ( TMPZ ) on the contraction of isolated guinea pig trachea induced by leukotrienes,histamine,prostagladin F2a , acetylcholine were observed. It was found that TMPZ exerts an inhibitory effect on the contraction induced by these asthmogenic mediators. It is non-competitive antagonist.
