Distribution of Hematoporphyrin Monomethyl Ether in Tumor-bearing Mice
- VernacularTitle:血卟啉单甲醚在荷瘤小鼠体内的分布
- Author:
Wenhui CHEN
;
Deyu XU
- Publication Type:Journal Article
- Keywords:
hematoporphyrin monomethyl ether;
hematoporphyrin derivative;
tumor-photochemo-diagnosis and photochemotherapy;
tissue distribution
- From:
Academic Journal of Second Military Medical University
1982;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
spleen(?)heart(?)muscle.The pharmacokinetics of PsD-044 in mice was fitted by an open three compartment model. The pharmacokinetic parameters calculated were shown to be essentially consistent with the determination of tissue distribution. It was also shown that PsD-044 can't pass through blood-brain barrier.