A Study of Kupffer Cell Phagocytic Function and Its Pathological Changes in the Rat with Experimental Obstructive Jaundice
- VernacularTitle:实验性阻塞性黄疸时枯否氏细胞吞噬功能及病理学变化的研究
- Author:
Rui LI
- Publication Type:Journal Article
- Keywords:
bile duct obstruction, extrahepatic;
Kupffer cells/UL;
peroxidase;
phagocytosis;
fibronectins
- From:Journal of Third Military Medical University
1984;0(02):-
- CountryChina
- Language:Chinese
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Abstract:
Pathological changes of Kupffer cells in number and ultrastructure were studied by means of colloidal carbon uptake, endogenous peroxidase cytochemistry, quantitative histology and ultrastructural stereologic morphometry at various time intervals (3,7,14,21,and 28 d) after common bile duct ligation. Kupffer cell phagocytic function and serum fibronectin opsonic activity were measured. The results show the morphological changes of Kupffer cells coinciding with their functional alterations. Alteration of Kupffer cell phagocytic function is mainly due to the changes of number and cellular activity of Kupffer cells.
