THE PROTECTIVE EFFECT OF BERBAMINE ON CEREBRAL INFARCTION MODEL IN RATS
- VernacularTitle:小檗胺对大鼠脑皮层梗塞的保护作用
- Author:
Lihua BAO
;
Fenglin LI
;
Wenhan LI
- Publication Type:Journal Article
- Keywords:
Cerebral infarctionlmodel;
Evans blue;
TTC;
Berbamine
- From:
Chinese Pharmacological Bulletin
1987;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
The cerebral infarction model was made according to Chen et al To evaluate the severity of infarction the quantity of Evan's blue was measured. The cerebral infarction size was determined by TTC stain. The results showed that ligating the right common carotid artery and the right middle cerebal artery and clamping the left common carotid artery could induce cerebral cortex in farction. Berbamine could decreased the level of Evan's blue and reduce the infarction size compared with control group. It suggests that berbamine possesses protective effect on experimental induced cerebral infarction.
