THE SCAVENGING ROLE OF OXYGEN FREE RADICALS BY SALVIA MILTIORRHIZA
- VernacularTitle:丹参的氧自由基清除作用
- Author:
Weidong YANG
;
Hongliang ZHU
;
Baolu ZHAO
- Publication Type:Journal Article
- Keywords:
Salvia Miltiorrhiza;
Electron paramagnetic resenance;
Spin trapping;
Oxygen free radicals
- From:
Chinese Pharmacological Bulletin
1987;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Using Xanthine-Xanthine Oxidase system to generate superoxide ani-on, using H2O2 -Fe2 + system to generate hydroxyl radical, the role of scavenging oxygen free radical by Miltiorrhiza was studied by electron paramagnetic resonance and spin trapping. The result suggested that the scavenging rate of hydroxyl radical by Salvia Miltiorrhiza injection is 65%, and that of superoxide anion is 100%. This result suggests that scavenging cytotoxic oxygen free radicals may be one of important pharmacological mechanism of Salvia Miltiorrhiza.
