EFFECT OF POLLEN ELEMENT FROM BUCKWHEAT, AND ISOCORYDINE ON THE GERBILS SUBJECTED TO CEREBRAL ISCHEMIA AND THEN REPERFUSION
- VernacularTitle:荞麦花粉水溶性黄酮部分、异紫堇定对沙土鼠脑缺血重灌流损伤的影响
- Author:
Linxian LI
;
Yumin ZHANG
;
Zican WANG
- Publication Type:Journal Article
- Keywords:
Pollen element from buckwheat;
Isocorydine;
Stroke index;
Mortality;
Cerebral ischemia;
Reperfusion
- From:
Chinese Pharmacological Bulletin
1987;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
After 45 min ligation of the gerbils' bilateral carotid arteries and then 24h reperfusion,the effects of water soluble Pollen flavone element from buckwheat, Isocorydine on the stroke index of 45 min cerebral ischemia followed by reperfusion 6h and the mortality of reperfusion 24h were evaluated .The results indicated that pollen element from buckwheat could decrease the stroke index and mortality rate dramatically, while Isocorydine had no effects.It was speculated that the beneficial effects of pollen element from buckwheat on cerebral damage following ischemia with reperfusion might be due to its depressing effect on the metabolism of free radicals.
