REGULATORY EFFECTS OF CPP ON CELL-MEDIATED IMMUNITY IN MICE
- VernacularTitle:党参多糖对小鼠细胞免疫调节作用
- Author:
Huiyan WANG
;
Meijun HAN
;
Sili JIN
- Publication Type:Journal Article
- Keywords:
Codnopsispilosula polysaccharidee ( CPP );
Macrophage phagocytose;
Clearance rate of charcoal partides;
E rosette;
Delayed type hypersensitivity (DTH);
Immunoregulation
- From:
Chinese Pharmacological Bulletin
1986;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Codnopsispilosula polysaccharides (CPP) , which administered intra-peritoneally 200mg/kg?d-1 for 5 d or 8 d in mice, enhanced thephagocytic activity of peritoneal macrophages on chiken RBC, the erythrocyte (E)rosette formation of thymus T lymphocyte and the clearance rate of charcoal particles in normal mice and antagonized the inhibition of E rosette formation and of peritoneal phagocytic activity caused by cyclophosphamide ( CY ) or hydrocortisone ( HCT ) . It inhibited the delayed type hypersensitivity ( DT H ) induced by DNCB and enhanced DT H induced by dexamethasons ( DMS ) . It has regulatory important signification in resisting decrepitude.
