EFFECT OF INTRACEREBROVENTRICULAR INJECTION OF TRH ON INTRAGASTRIC PRESSURE IN RATS
- VernacularTitle:侧脑室注射TRH对大鼠胃内压的影响
- Author:
Wenhua LIN
;
Jingxing ZHANG
;
Huixiu ZHANG
- Publication Type:Journal Article
- Keywords:
Thyrotropin-releasing hormone;
Dors motor nucleus of vagus;
Intragastric pressure;
Phasic contraction
- From:
Chinese Pharmacological Bulletin
1986;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
In the present study, the results were as follows: ( 1 ) Thyro-tropin-releasing hormone ( TRH ) injected into the intracerebroven-tricle increased intragastric pressure & evoked the phasic contraction of stomach significantly. ( 2 ) The increased response was decreased by bilateral destruction of dorsa. motor nucleus of vagus. ( 3 ) The increase was abolished completely by either vagotomy or atropine.The aforementioned results indicate that the action of dors. motor nucleus of vagus is partly involved the central mechanism of gastric movement induced by TRH & the vagal is the efferent pathway.
