ANTILIPID-PEROXIDATION EFFECT OF COENZYME Q10
- VernacularTitle:辅酶Q_(10)抗脂质过氧化作用
- Author:
Chaoshu TANG
;
Zhaoping LI
;
Shi CHENG
- Publication Type:Journal Article
- Keywords:
Coenzyme Q10;
Lipid peroxidation;
Myocyte;
Liposome
- From:
Chinese Pharmacological Bulletin
1986;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
In the isolated adult rat's ventricular myocytes and artificial bio-membrane-liposomes, the lipid peroxidation caused by generating system of free radicals (FeCl2 & ascorbic acid ) was significantly inhibited by Co Q10, and the inhibition effect of Co Q10 was both dose-and time-dependent. The results showed that Co Q10 had an antioxi-dation effect and served as a scavenger of free radicals at the level of membrane .