Effect of Intracerebral Injection of Substance P on Pain Threshold,Electroacupuncture Analgesia and Met-enkephalin Contents of Several Brain Areas in Rats
- VernacularTitle:脑内注射P物质对大鼠痛阈、电针镇痛和不同脑区甲啡肽含量的影响
- Author:
Xicheng LI
- Publication Type:Journal Article
- Keywords:
analgesia;
electro acupuncture;
Met-enkephalin;
substance P;
pain threshold;
areas in brain
- From:Journal of Third Military Medical University
1983;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Radioimmunoassay was used to determine the immunoreactive met-enkephalin (ir-MEK) contents of several brain areas.The pain threshold (PT) and the ir-MEK contents of striatum and hypothalamus increased markedly by intracerebro-ventricular (icv) injection of substance P (SP,1?g/10?1),no significant change of ir-MEK in hippocampus,and the increased ir-MEK contents and pain threshold were obviously deminished (P
