EFFECTS OF QUINIDINE, DAURICINE & TETRANDRINE ON REPERFUSION-INDUCED ARRHYTHMIAS IN THE RATS
- VernacularTitle:奎尼丁、蝙蝠葛碱、粉防己碱对大鼠复灌所致心律失常的影响
- Author:
Jianhua CHENG
;
Jiaqing QIAN
- Publication Type:Journal Article
- Keywords:
Quinidinc;
Dauricine;
Tetrandrine;
Reperfusion;
Arrh-ythmias
- From:
Chinese Pharmacological Bulletin
1987;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Five min coronary artery occlusion followed by reperfusion in rats could produce arrhythmias which were rapid in onset & of short duration. The incidences of VT & VF being 100% & 72% respectively. Quinidine & dauricine reduced the incidence & severity of VT significantly; and abolished VF. Tetrandrine could reduce the incidence of VF significantly, but it had no significant effect on the incidence of VT.
