EFFECT OF 4-PHOSP ATE-HYDROXYPIPERAQUINE ON THE ISOLATED AURICAL OF GUINEA PIG
- VernacularTitle:磷酸羟基哌喹对豚鼠心房肌的作用
- Author:
Husong LI
;
Gengsheng ZHAO
- Publication Type:Journal Article
- Keywords:
4-Phosphate-Hydroxypiperaquine;
Auricle;
Contra-ctility;
Functional refractory period;
Excitability;
Automaticity;
Ca~(2+);
Na~+
- From:
Chinese Pharmacological Bulletin
1987;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
The effect of 4 -Phosphate- lydroxypiperaquine ( PHPQ) on the phsiologic properties in isolated auricle of guinea pig was studied.Twenty minutes after PHPQ 30 ?mol/L was added, the contractility & dT/dtmax of the left atria of guinea pig were decreased to 74.4 ? ( SD ) 5.3%(n=6, P
