Clinical Significance of Infected Prostate Tissue in Patients with Benign Prostatic Hyperplasia.
10.4111/kju.2009.50.10.1014
- Author:
Hoon CHOI
1
;
Seung Chol PARK
;
Hee Jong JEONG
;
Ji Hyun JO
Author Information
1. Department of Urology, Wonkwang University School of Medicine, Iksan, Korea. uro94c@wonkwang.ac.kr
- Publication Type:Original Article
- Keywords:
Prostatic hyperplasia;
Prostatitis;
Inflammation
- MeSH:
Bacteria;
Bacterial Infections;
Calculi;
Humans;
Inflammation;
Male;
Prospective Studies;
Prostate;
Prostate-Specific Antigen;
Prostatic Hyperplasia;
Prostatitis;
Transurethral Resection of Prostate;
Urethra
- From:Korean Journal of Urology
2009;50(10):1014-1017
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Benign prostatic hyperplasia (BPH) and prostatitis are the most common benign diseases of the prostate gland and over time affect a significant majority of men. We evaluated the relation between BPH and infection in prostatic tissue in men who underwent transurethral resection of the prostate (TURP). MATERIALS AND METHODS: This prospective study included 63 consecutive patients diagnosed with BPH and scheduled for TURP. During the TURP, 1-2 g chips were collected after resection of the prostatic urethra, and specimens were transported to the laboratory in sterile saline. Homogenized specimens were incubated for 7 days. The patients were divided into 2 groups (group 1: culture positive, group 2: culture negative). We compared prostate volume, prostate calculi, serum prostate-specific antigen (PSA), International Prostate Symptom Score (IPSS), maximum flow rate (Qmax), post-void residual urine, and ratio of the transitional zone prostate to total prostate (transitional zone ratio). RESULTS: Mean age was 72 years and mean serum PSA was 4.36 ng/dl. Group 1 included 7 patients (11.1%) and group 2 included 57 patients (88.9%). There were no significant differences in prostate volume, prostate calculi, serum PSA, IPSS, Qmax, or post-void residual urine between groups, but the transitional zone ratio was higher in group 1 (45.4%) than in group 2 (30.3%) (p<0.05). CONCLUSIONS: About 11% of the prostate tissue cultures showed bacterial growth. The transitional zone ratio was higher in patients with bacteria growth. Bacterial infection may be related to benign prostatic hyperplasia.
