INFLUENCES OF PERFUSATE ION CONCENTRATION ON REPERFUSION ARRHYTHMIAS IN LANGENDORFF HEART OF RATS
- VernacularTitle:离子浓度对离体大鼠心脏再灌注性心律失常的影响
- Author:
Yulong LI
;
Shaoxuan FU
;
Yunshan LI
- Publication Type:Journal Article
- Keywords:
Langendorff heart of rat;
Reperfusion-induced arrhy-thmia;
Perfusate K~+;
Perfusate Ca~(2+);
Perfusate Mg~(2+)
- From:
Chinese Pharmacological Bulletin
1987;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Using method of orthogonal design we observed that low K+,high Ca2+ & low Mg2+ in perfusate produced the peak incidence of reperf-usion-indaced ventricular fibrillation & introduction of K+ & Ca2+ significantly affected the incidence & pnset of it, The appropriate prop-ortion of K+, ea2+ & Mg2+ in perfusate is the important effecting factor of reperfusion-induced arrhythmias in Langendorff heart of rats.
