EFFECTS OF CORYDALIS AMABILIS MIGO TOTAL ALKALOIDS; PHYSIOLOGIC PROPERTIES OF ISOLATED GUINEA PIG MYOCARDIUM
- VernacularTitle:夏天无总碱对豚鼠离体心肌生理特性的影响
- Author:
Min LIU
;
Gaohong FENG
- Publication Type:Journal Article
- Keywords:
Corydalis amabilis Migo;
Heart atrium;
Papillary muscles;
Myocardial contraction;
Functional refractory period;
Au-tomaticity
- From:
Chinese Pharmacological Bulletin
1987;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Corydalis amabilis Migo total alkaloids (COAMTA) possessed antihypertensive and vaso-dilatative action in animal experiments. Its effects on the physiological properties in isolated guinea pig papillary muscles & atrium preparations were described in this papar.10mg/L COAMTA markedly prolonged the functional refractory period(FRP) and inhibited epinephrine induced automaticity. Suppression of normal & abnormal automaticity and prolongation of FRP may contribute to the effectiveness of COAMTA on arrhythmia.
