Oxygen -derived Free Radicals Induced Cellular Injury in Superior Mesenteric Artery Occlusion Shock : Protective Effect of Super oxide Dismutase ( SOD)
- VernacularTitle:大白鼠肠系膜上动脉夹闭休克时SOD抗脂质过氧化损伤的研究
- Author:
Jianghuai WANG
- Publication Type:Journal Article
- Keywords:
Superoxide dismutase/PD;
Free radicals;
Malondialdehyde;
Artery , superior mesentery;
Shock
- From:Journal of Third Military Medical University
1984;0(02):-
- CountryChina
- Language:Chinese
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Abstract:
Intraaterial injection of superoxide dismutase (SOD)15000U/kg 15 min before releasing the obstruction is given . 35 rats are divided into 3 groups : group 1, 7 for control; group 2,14 for releasing the obstruction for 1 h ; in which (7 as 2A , 7 as 2B ) 2B are given SOD ; group 3 , 14 for releasing the obstruction for 2 h , in which (7 as 3a , 7 as 3B ) 3B given SOD . The results show : the content of malondialdehyde (MDA) in bowel , and heart tissue in 2A increases 66% and 55% (p 05) vis group 1 ; contents of MDA in bowel, heart, liver , and lung tissues in 3A increase 126% , 69%,36%, and 28% (p
