THE EFFECTS OF INTRAVENEOUS AMINOPHYLLINE INFUSION ON THE VENTILATION AND LEFT HEART FUNCTION IN THE PATIENTS WITH COPD AND COR PU-LMONALE
- VernacularTitle:静脉滴注氨茶碱对慢性阻塞性肺病、肺心病患者通气功能及左心功能的影响
- Author:
Qingnan DENG
;
Yong LIU
;
Xiaoming KANG
- Publication Type:Journal Article
- Keywords:
Aminophylline Chronic obstructive pulmonary disease Cor pulmonale
- From:
Medical Journal of Chinese People's Liberation Army
1982;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
12 cases of COPD with cor pulmonale and 5 health volunteers were observed while load dose of aminophylline (6mg/kg) was infused intraveneously.LVEF,LVER were measured by 113In-nuclide before and after administration,and FEV1.0,FVC,and arterial blood gas were determined.Serum concentration of theophylline was measured simultaneously.The results showed:(I) In COPD and cor pulmonale patients 10/12 (85%) showed abnormal LVEF,LVER without evidence of coronary heart disease.The results suggested that left ventricular performance were impaired.(2)After load dose of ami-nophylline infusion the left ventricular performance and pulmonary ventilation were improved synchronously.It suggested that aminophylline may be a drug of choice in the stable state of these patients.
