EFFECT OF HEPATIC STIMULATOR SUBSTANCE ON CELLS GROWTH IN VITRO
- VernacularTitle:肝生长剌激物质对肝细胞增殖作用的体外观察
- Author:
Xiangquan LI
- Publication Type:Journal Article
- Keywords:
hepatic stimulator substance;
cell line;
cell culture;
growth factor
- From:
Academic Journal of Second Military Medical University
1985;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
The effects of hepatic stimulator substance (HSS) extracted from wealing rats on 4 kinds of cell lines are reported.In LW13 normal liver cell line, HSS significantly increased the incorporation of 3H-TdR into liver cells, but it had no effect oo K562 erythrokukcmia cell line and primary culture of rabbit epidermal cells, the latter can be stimulated by keratinocyte growth factor at a dose of 38?g/ml. Study of response of SMMC-7721 human hepatoma cell line to HSS revealed a dose-dependent decrease in 3H-TdR incorporation.