Levels of Lipid Peroxide in Plasma and CSF Observed in Acute Cerebral Vascular Disease
- VernacularTitle:急性脑血管病血浆及脑脊液中脂质过氧化物含量的观察
- Author:
Caimei ZHENG
- Publication Type:Journal Article
- Keywords:
Cerebral arteries diseases;
Malondialdehyde;
Lipid peroxides
- From:Journal of Third Military Medical University
1988;0(06):-
- CountryChina
- Language:Chinese
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Abstract:
The clinical features and plasma malondialdehyde(MDA) contents were studied in 91 patients with acute cerebral vascular disease (ACVD). The cerebrospinal fluid (CSF) MDA contents were also measured in 51 of them. The MDA contents increased significantly more than that of the control group. The difference of CSE MDA between the disease group and control was more significantly than that of plasma. It may be due to the fact that the CSE MDA level reflects the severity of lipid peroxidative reaction (LPR) in brain directly, whereas plasma MDA level reflects the severity of systemic LPR. The dynamic change of plasma MDA is closely related to the outcome of the disease. The plasma MDA decreases in ameliorated patients, but increases in the aggravated. The measurement of palsma MDA may be used as an indicator to predict the prognosis of ACVD.
