EFFECTS OF THE COMPOUND OF SILYMARIN AND FENOFIBRATE ON HYPERLIPIDEMIC RATS
- VernacularTitle:水飞蓟总黄酮与Fenofibrate合用对大鼠高血脂症的影响
- Author:
Decai HUANG
;
Shijie QIU
- Publication Type:Journal Article
- Keywords:
Silymarin;
Fenofibrate;
Lipoprotein Cholesterol;
Hyperlipidemia
- From:
Chinese Pharmacological Bulletin
1986;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
After the rats with hyperlipidemia were orally treated with the compound of Silymarin and Fenofibrate for 3 weeks, the blood levels of TC, LDL-c, VLDL-c in serum were significantly decreased. Especially, the concentration of HDL-c was greatly increased. The contents of TC and TG in the rat' s liver were also significantly decreased. It was also found that the effects of the compound of Silymarin and Fenofibrate on the level lipoprotein and TC or TG in liver were more significantly that of Silymarin or Fenofibrate alone
