Morphological Differences in the Tight Junction of the Freeze-etched Alveolar Epithelium and Capillary Endothelium in Normal Rat with Morphometry
- VernacularTitle:定量观察大鼠肺泡上皮细胞及毛细血管内皮细胞紧密连接冷冻蚀刻的形态学差异
- Author:
Guobiao ZHU
- Publication Type:Journal Article
- Keywords:
Freezing etching/method;
Capillaries/cytology;
Pulmonary alveolo/cytology
- From:Journal of Third Military Medical University
1983;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
One hundred and fourteen tight junctions of the alveolar epithelium and capillary endothelium in rat lungs were studied with morphometry by freeze-etching technique. Statistically, there was highly significant difference in the following five aspects between alveolar epithelium and capillary endothelium. ( 1 ) Number of strands (4.54?1.86; 2.64?0.67) . (2) Width of tight junction (0.399? 0.268; 0.175?0.075 micron) . (3) Area of tight junction (0.353?0.35; 0.11 ? 0.098 square micron) . (4) Total length of strands (3.97?3.5; 1.47?0.916 micron) . (5) Morphology of strands and pattern of the tight junction. However, there was no significant difference in density of strands of tight juuctions between the alveolar epithelium and capillary endothelium. The functional significance of these differences between alveolar epithelium and capillary endothelium was discussed in detail.
