EFFECTS OF LAO SHAN POLYSACCHARIDE P ON THE METABOLISM OF ACETYLATED LDL BY MACROPHAGES
- VernacularTitle:老山云芝多糖P对巨噬细胞代谢乙酰低密度脂蛋白的影响
- Author:
Wu SONG
- Publication Type:Journal Article
- Keywords:
Lao Shan polysaccharide P;
Macrophage;
Scavenger receptor;
Cholesterol;
Acetyated low density lipoprotein
- From:
Chinese Pharmacological Bulletin
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
It was found that the Lao Shan polsaccharide P, one of the chemical components of polystictus versicolor increased the number of acetylated low density lipoprotein ( acLDL ) receptorsin the macrophages and stimulated the binding, internalization and degradation of (125I ) acLDL by the macrophages in vitro. The effect on cell degradation of ( 125I ) acLDL was dose-effect. At 100?g/ ml of the Lao Shan polysaccharide P, the effect was maximum and the degradation of ( 125I ) acLDL increased 77% ( P
