PULMONARY FAT EMBOLISM INDUCED BY FORCED IMMOBlLIZATION IN RABBITS
- VernacularTitle:制动应刺激造成兔肺脂肪栓塞的实验研究
- Author:
Hong XUE
- Publication Type:Journal Article
- Keywords:
fat embolism;
forced immobilization stress;
lipoprotein lipase;
rabbits
- From:
Academic Journal of Second Military Medical University
1981;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
In the present study, forced immobilization induced-pul-monary fat embolism as an experimental model was developed for the first time in rabbits.The area of emboli was calculated by an electronic caculator.At the same time, the activities of lipoprotein lipase in post-heparin plasma (PHP-LPL) and the concentrations of free fatty acids(FFA)were measured,The determination of plasma catecholamines, the analysis of blood gas, the observation of pulmonary morphology (including ultrastructure)were also carried out,It was found that forced immobilization for 5h could induced pulmonary embolism in rabbits, accompanied by the elevation of PHP-LPL and FFA in pulmonary circulation, hypocapnia, and the tendency of surfactant insufficiency.The results suggest that the disorder of homeostasis caused by stress is strong enough to induce pulmonary embolism without the participation of fracture
