EFFECTS OF FOOT-SHOCK ON ?-ENDORPHIN AND NEUROTENSIN-LIKE IMMUNOREACTIVITY IN THE BRAIN AND PITUITARY OF RATS
- VernacularTitle:电击足底应激时大鼠脑和垂体?内啡肽和神经降压素样免疫活性物质含量的变化
- Author:
Changlin LU
- Publication Type:Journal Article
- Keywords:
foot shock;
stress;
hypothalamus;
pituitary;
?-endorphin;
neurotensin;
rats.
- From:
Academic Journal of Second Military Medical University
1981;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
The effects of foot-shock (FS) on ir-?-EP and ir-NT in the brain and pituitary of unanaesthetized rats were studied by means of radioimmunoassay (RIA). It was found that the content of ir-?-EP decreased significantly in pituitary and increased in hypothalamus, and the content of ir-NT increased both in pituitary and hypothalamus 2 min after FS. However, ir-?-EP increased in pituitary and decreased in hypothalamus, and ir-NT decreased both in pituitary and hypothalamus 20 min after FS. These results indicate that at the early period of FS induced stress, the release of ir-?-EP may be increased from pituitary, and ir-NT may be decreased from both pituitary and hypothalamus.
