EFFECTS OF THYROTROPHIN-RELEASING HORMONE ON SURVIVAL AND ?-ENDOPHIN RELEASE IN SCALDED RATS
- VernacularTitle:促甲状腺素释放激素对烫伤大鼠存活率和?-内啡肽含量的影响
- Author:
Sen HU
- Publication Type:Journal Article
- Keywords:
TRH Burn Shock ?-EP
- From:
Medical Journal of Chinese People's Liberation Army
1982;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
The effects of thyrotrophin releasing hormone(TRH) given 0.5h after injury on survival and ?-endorphin release in scalded rats (about 30% TBSA, 20s in 100℃ water) were studied. The results showed tenfold increase of ?-endorphin-like immunoreactivity (ir-?-EP) in the plasma and the pituitary 2h after scald, while in the hypothalamus ir-?-EP did not rise above control until 6h after scald. 24h after scald, survival in rats given TRH was 46.7% and those given saline was 6.7% (P
