STUDY ON HYPOTENSIVE CONSTITUENT OF RHODODENDRON MOLLE ( BI. ) G.DON
- VernacularTitle:羊踯躅降压成分的研究
- Author:
Jinming CHEN
;
Jifen ZHANG
;
Yanbin ZHANG
- Publication Type:Journal Article
- Keywords:
Rhododendron molle ( BI. ) G.Don. Hypotensive constituent;
Cholinergic nerve system.
- From:
Chinese Pharmacological Bulletin
1986;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Four constitunets were isolated from the flower of Rhododendron molle ( BI. ) G. Don. One of these was named Rdl.The acute LD50 of Rdl in mice ( iv ) was found to be 4742 ug/kg.The hypotensive effect of Rdl was studied in various anesthesized animals. In cats, the dosage of 100, 300 and 500 Hg/kg of the Rdl ( iv ) reduced the blood pressure by 10:9% ( P