THE ULTRASTRUCTURAL CHANGES IN THE MYOCARDIA IN PATIENTS SUFFERING FROM PRIMARY DILATED-CONGESTIVE CARDIOMYOPATHY
- VernacularTitle:原发性扩张型心肌病心肌超微结构变化
- Author:
Chuanjing PAN
- Publication Type:Journal Article
- Keywords:
Cardiomyopathy Uitrastructure
- From:
Medical Journal of Chinese People's Liberation Army
1983;0(05):-
- CountryChina
- Language:Chinese
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Abstract:
The histopathological and ultrastructural changes in myocardial biopsy material of 6 patients suffering from primary dilated-congestive cardiomyopathy (DCM P) were studied with following findings: 1. In the hypertrophic myocardial cells there were proliferation and hypertrophy of mitochondria, many of which acummulated beneath the cell membrane, producing finger-like projections as well as increasing the cellular volume. The contractile elements of myocardia did not increase in number and showed so- me degenerative changes. 2. Degeneration of myocardia menifested mainly as condensation of myofila-ments, and seemed to be the contributing factor to impairment of myocardial contraction. Hypertrophy and degeneration seemed to be two different stages of the same pathology as transitional changes from one to another were found. 3. Edema, which might proceed to cellular lysis or necrosis, was another manifestation of degeneration of the myocardium. These findings gave the morphologic basis of impairment of myocardial contraction in primary dilated-congestive cardiomyopathy.
