EFFECT OF NALOXONE ON ELECTROCARDIOGRAM IN BURNED RATS
- VernacularTitle:纳洛酮对烫伤大鼠心电图的影响
- Author:
Jun YANG
- Publication Type:Journal Article
- Keywords:
naloxone;
endogenous opiate like substance;
opiate receptors;
electrocardiography;
burns;
rats
- From:
Academic Journal of Second Military Medical University
1981;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Twenty male wistar rats were divided into naloxone group and control group, and their backs were dipped into boiling water, which resulted in deep Ⅱ or Ⅲ degree burn of about 20% of BSA.Naloxone or normal saline were injected into lateral ventricle and electrocardiogram (ECG) was recorded every 30 minutes.The results showed that the ECG of burned rats had not only a prolonged P-P, P-R, QT interval and QRS, but also an elevated ST segment and R wave. These changes were greatly delayed in the naloxone group (p
