HYPERLIPIDEMIA IN COPPER DEFICIENCY RATS
- VernacularTitle:缺铜致大鼠高脂血症的研究
- Author:
Lirui JIANG
;
Shouxun WANG
;
Huansheng HUANG
;
Yonghua YUAN
;
Fengxiang SUN
- Publication Type:Journal Article
- Keywords:
copper deficiency hyperlipidemia rat
- From:
Acta Nutrimenta Sinica
1956;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
In order to investigate the interelationship between copper deficiency and lipidemia, an experiment was done in weanling rats fed normol and copper deficient diet for one month. At the end of experimental period, the growth rate, the contents of copper, zinc, cholesterol and triglyceride in plasma and the activity of monoamine oxidase (MAO) in plasma were measured. The differences between the two diets were compared by student's test and the relation between plasma copper and plasma cholesterol or MAO was ascertained by regression analysis.The results showed that a lower body weight gain and a highly significant hypercholesterolemia were found in copper deficiency rats and the plasma cholesterol concentration correlated reversely with the plasma copper (r = -0.724, p