EFFECTS OF FU-TZE "801" ON SURVIVAL AND MICROCIRCU- LATORY CHANGES IN BURN SHOCK RATS
- VernacularTitle:川附子“801”对烫伤休克大鼠存活率和微循环的影响
- Author:
Meijuan XU
;
Xilin LIAO
- Publication Type:Journal Article
- Keywords:
scald-burn shock;
Microcirculation;
Survival;
Platelet aggregation;
Rats:
- From:
Chinese Pharmacological Bulletin
1987;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
The antishock properties of Fu-tze "801" , an active fraction isolated from the root of Aconite,were studied on burned rats. The rats were given 65-70% TB'SA second degree scalds. All animals died in a short time postburn. Using this rat model, it was found that the marked spasmodic rhythmic constriction in arterioles occurred and the microierculatory flow state showed pronounced derangements in the me-senteric microcirculation, and platelet aggregate increased in circulating blood.After treatment with Fu-tze "801" , the survival and the mirocirculation were improved in the scalded rats, these findings suggest that Fu-tze "801" affords the antishock action on rats after a major scald burn.
