A Preliminary Study on Clonorchis sinensis Infectionin Rhesus Monkeys
- VernacularTitle:恒河猴感染华支睾吸虫的初步观察
- Author:
Fuchun LAI
- Publication Type:Journal Article
- Keywords:
Clonorchis sinensis;
Clonorchiasis;
Rhesus monkey
- From:Journal of Third Military Medical University
1984;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
The infection of Clonorchis sinensis in two rhesus monkeys (Macaca mulatta, RH30 and RH48) was established by orally giving the metacercariae of the parasite (from Pseudorasbora parva from Sichuan) . Another monkey (RH405) served as control. The two monkeys, RH30 and RH48, were killed 30 and 48 days after infection respectively. The recovery rate of the parasite was 9.9% in RH30 and 31.59% in RH48. The worms recovered were the mature form, and mature eggs were found in the feces of the 2 monkeys 27-30 days after infecation.The pathological findings of clonorchiasis in the early stage in rhesus monkeys were eosinophilia (30 days after infection) , intralesional plasma cell infiltration (48 days after infection) , and adenomatous hyperplasia of the biliary epithelium in associatoin with an increase of acid mucin production. The significance of the last manifestation in relation to the stone formation was discussed.
