EFFECTS OF CORYDALIS TURTSCHANINOVII F.YANHUSUO (LARGE LEAF TYPE) ON EXPERIMENTAL MYOCARDIAL ISCHEMIA
- VernacularTitle:大叶延胡索的抗实验性心肌缺血作用
- Author:
Yongwen QIN
- Publication Type:Journal Article
- Keywords:
rhizoma corydalis turtschaninovii f.yanhusuo (large leaf type);
coronary blood flow;
myocardial ischemic necrosis;
myocardial infarction;
disease models,animal
- From:
Academic Journal of Second Military Medical University
1982;0(02):-
- CountryChina
- Language:Chinese
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Abstract:
In this paper, the effects of rhizoma corydalis turtschaninovii f.yanhusuo (large leaf type5 LLYH) on experimental myocardial ischemia and coronary blood flow are reported.LLYH was showed to be active in increasing the tolerance of mice to monobaric hypoxia and prolonging survival time of the animal under the high oxygen consumption condition induced by large dose of isoproterenol.It decreased the severity of myocardial ischemic necrosis induced by large dose of isoproterenol in mice and reduced the extent of myocardial infarction in Wistar rats 12 h after ligation of the root of th,e left coronary artery.In anesthetized open chest cats, coronary blood flow was increased by LLYH infusion with slight decrease in heart rate and blood pressure.
