Changes of Serum Creatine Kinase after Bullet Fragment Injury in Dogs
- VernacularTitle:小弹片致伤后早期血清肌酸激酶反应
- Author:
Lichao ZHENG
- Publication Type:Journal Article
- Keywords:
Creatine kinase;
Fragment wound
- From:Journal of Third Military Medical University
1986;0(S1):-
- CountryChina
- Language:Chinese
-
Abstract:
The reaction of serum creatine kinase (SCK) to skeletal muscle injuries is very sensitive and specific. The changes of SCK levels were studied in 40 adult dogs after their hind legs were wounded with small bullet fragments. In addition, the relations between the changes of SCK levels and the mass and shape of the fragments and the severity of the tissue damage were also observed.It was found that SCK level increased significantly 30 minutes after injury. It continued to increase and reached the peak in 6 hours. Pathological studies revealed that necrosis occurred in the skeletal muscle cells in the first 6 hours after injury. The increasing of SCK level was in good agreement with the exten-siveness of the tissue damage. There was also a definite linear relationship between the SCK reaction and the amount of kinetic energy absorbed by the tissues, and the amount of the dead tissues excised.Our results prove that the severity of tissue damage resulting from fragment injury is closely related to the shape, mass and impact velocity of the fragments.
