INFLUENCE OF SELENIUM ON THE SYNTHESIS OF NUCLEIC ACIDS IN HUMAN AMNION CELLS AND MONKEY KIDNEY CELLS
- VernacularTitle:硒对人羊膜细胞和猴肾细胞核酸合成的影响
- Author:
Dongling ZHAO
;
Hongyuan ZHANG
- Publication Type:Journal Article
- Keywords:
selenium synthesis of nucleic acid human amnion cell monkey kidney cell
- From:
Acta Nutrimenta Sinica
1956;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
The effect of selenium on the synthesis of nucleic acids in human am-nion cells and monkey kidey cells was studied by the techniques of cell culture and radioisotope assay. The cells were cultured in a medium containing varied dosages of sodium selenite for 24 hours at 37℃ in a CO2 incubator (5% CO2), then 3H-labeled precursors of DNA and RNA were added. The synthetic activity of DNA and RNA was determined by assaying the incorporation amount of radioisotope. The result suggested that selenium can promote intracellular DNA and RNA synthesis and may be essential to cell growth.