ANTIINFLAMMATORY, ANTIPYRETIC AND ANALGESIC EFFECTS OF SUDOXICAM
- VernacularTitle:国产湿痛喜康的抗炎解热和镇痛作用
- Author:
Xiurong JIA
;
Wencai JIAO
;
Wenshu WEI
;
Mingzhu CHEN
;
Shuyun XU
- Publication Type:Journal Article
- Keywords:
Sudexicam;
Antiinflammatory;
Antipyretic;
Analgesic
- From:
Chinese Pharmacological Bulletin
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
This paper describes the anti-inflammatory, antipyretic and analgesic effects of Sudoxicam ( Sud) synthesized by Shenyang Pharmaceutic College.Sud is found to possess significant anti-inflammatory, antipyretic and analgesic quality in such animal models as carrayeenan-induced paw oedema ( ED50=5.26mg/kg ) , tylolinduced ear oedema in mice, adjuvant-induced arthritis in rats, yeast-induced fever in rats, acetic acid-induced arithing ( ED50= 5.0mg/kg ) and hot plate-induced pain reaction in mice.
