FUNCTIONAL CHANGES IN RAT LIVER MITOCHONDRIA DURING THE EARLY PHASE OF BURN INJURY
- VernacularTitle:大鼠烫伤早期肝线粒体功能的改变
- Author:
Xuemin WANG
- Publication Type:Journal Article
- Keywords:
burn mitochondria oxidative phosphorylation respiratory control rate(RCR) succinic dehydrogenase (SDH) cytochromes
- From:
Academic Journal of Second Military Medical University
1981;0(03):-
- CountryChina
- Language:Chinese
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Abstract:
Using succinate as a substrate, the respiratory control rates (RCR's) of liver mitochondria of burned Sprague-Dawley rats (male, 20 percent of burned body surface area,III degree burn) were increased 15,30, 45, and 60 min after burn, the peak being at 30 min after burn (the sham group as control).In comparison with the sham group, the specific activity of succinic dehydro-genase was slightly decreased and the activities of cytochrome b and c + c1 were decreased significantly 30 min after burn.