Changes of Amino Acid Absorption through Small Intestines in Rats with Burn Injury
- VernacularTitle:大鼠烫伤后小肠氨基酸吸收的变化
- Author:
Luyuan XIAO
;
Xiaolin JIN
- Publication Type:Journal Article
- Keywords:
Ammo acid transport;
Intestine;
Na+-K+-ATPase;
Burn
- From:Journal of Third Military Medical University
1983;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
37% TBSA third degree burns was inflicted to rats and they were decapitated on the third day postburn.The 3H-proline absorption ratio of the everted small intestine of the burn group (1.87?0.27) was significantly lower than that of the control group (2.35?0.49) In the burn group,the ATPase activity of the small intestinal mucosa was 5.61?2.27 nmole/min/mg protein,and the Na+-K+-ATPase activity was 2.86?0.83 nmole/min/mg protein,while they were 9.63?1.04 nmole/min/mg protein and 5.36?0.95 nmole/min/mg protein in the control group respectively.Thus,it was apparent that the two activities decreased markedly in the rats with burn injury It was found that the amino acid absorption ratio was positively correlated with the activity of Na+-K+-ATPase of the small intestine mucosa in the burn group as well in the control group.The relative coefficient was 0.744 p(1) 0.025 in the control,and 0.776 p(1) 0.025 in the burn group.It suggests that the decrease of amino acid absorption ratio in the burn group is likely due to the decreased activity of Na+-K+-ATPase activity.
