STUDY ON ANTIBODY AGAINST LSP IN SERA OF PATIENTS WITH VIRAL HEPATITIS BY THE METHOD OF RADIOIMMUNOPRECIPITATION
- VernacularTitle:放射免疫沉淀法对病毒性肝炎患者血清中抗-LSP的探讨
- Author:
Changqing HE
;
Mengdong LI
;
Maoping CHENG
;
Zhiyong ZHENG
;
Hengguang YE
;
Juyou DENG
- Publication Type:Journal Article
- From:
Medical Journal of Chinese People's Liberation Army
1983;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
A specific and sensitive radioimmunoprecipitation method was used to detect antibody against liver-specific membrane lipoprotein (LSP) in the sera of 182 patients with viral hepatitis, HBsAg chronic carriers and liver cirrhosis and 40 patients with other diseases as control. The results showed that the highest frequency of anti-LSP was noticed in the patients with severe hepatitis (15 out of 16 cases, 93.8%), and in the patients with chronic active hepatitis, acute viral hepatitis, chronic persistent hepatitis, cirrhosis and other diseases and in the HBsAg chronic carriers the incidences were 83.6%(41/49 cases), 66.2% (43/65), 63.6%(14/22), 55.0%(11/20), 5%(2/40) and 10%(1/10) respectively. The frequencies of anti-LSP in the patients with various types of viral hepatitis were significantly higher than those in the HBsAg chronic carriers and in the patients with other diseases (P
