THE PREPARATION, PROPERTIES AND CLINICAL USE OF d-KETAMINE HYDRO-CHLORIDE
- VernacularTitle:盐酸右旋氯胺酮的制备及其药理试验和临床使用的观察
- Author:
Shizhong TU
- Publication Type:Journal Article
- Keywords:
ketamine anesthesia pharmacology, clinical
- From:
Academic Journal of Second Military Medical University
1982;0(01):-
- CountryChina
- Language:Chinese
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Abstract:
In this paper, we reported the method and the results for resolution of d-keta-mine hydrochloride with DTA reagent .The optical purity of d-ketamine hydrochlori-de is coordinative with its standard compound.The yield is 35% based on d-ketamine hydrochloride.This compound had been used in 43 patients clinically and obtained good results The dosage was rather smaller and lesser side effects, such as illusion,eyeball quiver and muscular tension. Especially, when the drug is used with pethdine and promet-hazine as complex anesthesia,patients will get better effect. Although the blood pressure and heart rate of patients slightly increased, it is suitable to patients with bleeding and wound.
