A PATHOLOGIC OBSERVATION OF EXPERIMENTAL THOERAPIES AFTER LETHAL DOSE MUSTURD GAS POISONING IN DOGS
- VernacularTitle:家犬在大剂量芥子气全身吸收中毒实验治疗后的病理观察
- Author:
Zhenhua LIU
- Publication Type:Journal Article
- Keywords:
musturd gas poisoning pathology
- From:
Academic Journal of Second Military Medical University
1985;0(05):-
- CountryChina
- Language:Chinese
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Abstract:
Thirty male dogs poisoned by lethal dose (21 mg/kg LD) of musturd gas were treated by 4 kinds therapeutic programs and observed by pathological examinations.The results showed that the 3rd therapeutic program was the best one.The survival rate of dogs reached 90.9%.The clinical therapeutic effects were supported by histopathological observation. The mucous epithelia of small bowel, spleen, lymph nodes, bone marrow, adrenal glands and testes, all of these tissues and organs were predominantly restord and regenerated after the 3rd therapeutic program treatment within 2 weeks.However, some problems require further research such as the restoration of immune function and the cortical functional changes of adrenal glands.Observations supplied histopathological evidences to improve further therapeutic program.
