PLASMA FIBRONECTIN LEVELS IN BURN INJURIES
- VernacularTitle:烧伤后血浆纤维结合蛋白的变化
- Author:
Zhiyong SHENG
- Publication Type:Journal Article
- From:
Medical Journal of Chinese People's Liberation Army
1983;0(05):-
- CountryChina
- Language:Chinese
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Abstract:
Plasma fibronectin (Fn) was determined in 180 healthy individuals. No significant difference was found between males and females; therefore the values were pooled. The mean value was 286.94?51.35 ?g/ml. In 16 burn patients, with burn extent ranging from 30% to 95%, plasma Fn was determined sequentially. It was found that there was a significant lowering in plasma Fn value in all cases on the postburn day 1 (112.56-173.04 ?g/ml) and postburn day 2 (44.03-218.4 ?g/ml). It returned to within normal range in 13 survivors on the postburn day 6. In 3 non-survivors, plasma Fn decreased progressively before death. In another 9 patients with minor burns (3%-25%TBSA), plasma Fn values were all within normal range on the postburn day 1.The causes of reduction of plasma Fn in patients with major burn injuries, as well as its relationship with the function of the monocyte-phagocyte system, were briefly discussed. The results of the present study suggests that the concentration of Fn in plasma might serve as an important prognostic index in the burn patients.
