STUDIES ON THE ANTICARCINOGENIC EFFECTS OF POLYSACCHARIDE FROM LAO SHAN POLYSTICTUS VERSICOLOR
- VernacularTitle:老山云芝多糖抗肿瘤作用的研究
- Author:
Yusen YAN
;
Jinsheng WANG
;
Minghu CHEN
;
Nansheng PAN
- Publication Type:Journal Article
- From:
Medical Journal of Chinese People's Liberation Army
1982;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Polysaccharide from Lao Shan Polystictus versicolor possesses a significant inhibitory effect on transplanted S180 in ICR mice, and the inhibition rate after intraperitoneal injection of 10 mg/kg of the drug was 60-70%. Oral administration in certain dosage could also inhibit tumor growth.Polysaccharide was given intraperitoneally one week before the transplantation of ascitic sarcoma S180 It showed that the polysaccharide could prevent the growth of ascitic S180 effectively and prolong the life span of the mice. Peritoneal injection of the polysaccharide could enhance the capacity of macrophages to release H2O2 and of the spleenic lymphocytes to take 3H-TdR. It has been demonstrated that polysaccharied from Lao Shan Polystictus versicolor was not cytotoxic, and its anticarcinogenic effect was host mediated.
