Preparation of Sodium salicylate-borate & Its Mycostatic Effect
- VernacularTitle:硼合水杨酸钠的合成及其对真菌抑制作用的初步研究
- Author:
Gtmlong TONG
;
Zhenju WANG
- Publication Type:Journal Article
- From:Journal of Third Military Medical University
1983;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Sodium salicylate-borate is a complex salt easily prepared by the reaction of salicylic acid and borax at 40-50℃. A three-color point with Rf values of 0.72, 0.58, and 0.48 respectively was obtained on the thin layer chromatography. The maxium absorbent peak of this complex salt (20?g/ml) was at 300 nm. determined with the ultraviolet spectrophotometer scanner.The mycostatic effect of this complex salt varies with its concentrations. It is effective against the superficial infections with the concentration of over 1250 ?g/ml; and 2500?g/ml is necessary for the treatment of deep fungus infections.
