PRELIMINARY OBSERVATION ON T LYMPHOCYTES IN PERIPHERAL BLOOD OF PATIENTS WITH CHRONIC ATROPHIC GASTRITIS AND GASTRIC CANCER BY DEMONSTRATION OF ACID ?-NAPHTHYL ACETATE ESTERASE
- VernacularTitle:用酸性?-醋酸萘酯酶显示法观察萎缩性胃炎与胃癌患者T淋巴细胞的初步结果
- Author:
Jie ZHANG
;
Weiwen LIU
- Publication Type:Journal Article
- From:
Medical Journal of Chinese People's Liberation Army
1982;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
A study of the peripheral blood T lymphocytes of patients with chronic atrophic gastritis (mainly of B type) and gastric cancer was undertaken by demonstrating the acid ?-naphthyl acetate esterase in lymphocytes as a T cell marker. A scoring method was also designed by the authors to estimate the esterase activity according to the size and number of the esterase particles. The T lymphocyte levels, i.e. ANAE%, of gastric cancer (46.2?1.87%) and chronic atrophic gastritis (54.4?1.48%) were significantly lower than that of normal controls (72.7?5.9%). The T lymphocyte levels of gastritis patients, however, were significantly higher than that of cancer patients. Based on the above findings, it is suggested that the changes of cell-mediated immunity may play a role in the etiopathogenesis and progression of B type atrophic gastritis.
