A STUDY ON THE ACTIVE PRINCIPLE OF POLYALTHIA NEMORALIS II. THE SYNTHESIS OF NATURAL OCCURRING METALLIC COMPOUND ZINCPOLYANEMINE
- VernacularTitle:陵水暗罗有效成分的研究 Ⅱ.暗罗素的合成
- Author:
Bingxiang XU
- Publication Type:Journal Article
- From:
Academic Journal of Second Military Medical University
1981;0(03):-
- CountryChina
- Language:Chinese
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Abstract:
Zincpolyanemine, which has been isolated from the root of polyalthia nemoralis A. et DC.exhibiting antimalarial activity against Plasmodium berghei, is a natural occurring metallic compound. Its chemical structure has been determined as the zinc salt of 2-mercaptopyridine N-oxide by means of synthesizing by five steps starting with 2-aminopyridine. The mp, IR and HMR spectra of the synthetic product coincide with those of the natural zincpolyanemine.